Your All-In-One Fluid Control Solution for Microfluidics

Smooth, accurate pressure control
Compact, self-contained unit
Fully programmable
Integrated with vivoChip

vivoVerse's vivoCube®+ is the latest version of our popular vivoCube microfluidics controller used in labs worldwide. Reengineered from the ground up, it provides users with an all-in-one solution for  delivering, smooth accurate pressure driven flow for their experiments.  It features two independently controllable pressure outputs supplied by an internal pump to drive flow from different liquid reservoirs, or supply fast, accurate pressure stimuli. The vivoCube+ is fully portable and more compact than other microfluidic flow controllers to allow it to fit in anywhere on your benchtop. No PC is required. Users can program virtually any series of pressure sequences directly on the unit using the intuitive vivoCubeOS and walk away.

The vivoCube+ continues to be ready out-of-the-box for use with our vivoChip microfluidic devices, with pre-programmed pressure cycles that have been optimized to load and immobilize C. elegans and other nematodes of all stages for high resolution imaging. However, the vivoCube+ is suitable for many more applications. Contact us to find out if it can work for you.

Key Benefits

Multiple applications

Microfluidics for cells, organoids, model organisms, droplet generation, and many more

Pressure or flow control

Precise regulation of pressure or flowrate output with vivoFlow

Dual channel output

Independent control of 2 channels with different flow conditions


Create flow cycle programs for your specific applications, or select from a library of optimized presets

Compact, sleek design

Built-in pump and intuitive user interface packed in a portable case

Future advanced features

APIs for LabVIEW and MATLAB and other features via future updates

vivoCube+ & vivoFlow: Your all-in-one fluid control solution for microfluidics

The vivoCube+ can be paired with our vivoFlow flow sensors for precisely calibrated, smooth delivery of liquids to your microfluidic setup. The vivoFlow has closed loop monitoring and control of fluid delivery over a wide range of flow rates and volumes down to >1µL/minute and is compatible with most chemicals, making it suitable for a multitude of microfluidics applications.

vivoCube+ and vivoChip for nematode imaging

The vivoCube+ has been designed to work in tandem with our vivoChip microfluidic devices for rapid high-resolution imaging of worm populations. See how it can help accelerate your experiments with C. elegans and other nematodes.

Other applications

The vivoCube+ and vivoFlow are highly suited to a wide variety of microfluidics applications such as:

Perfusion for cell cultures

Perfusion for organ-on-a-chip systems

Pulsatile flow generation

Droplet generation

Automatic reagent distribution

Nanoparticle syntheses

System features


Pressure range (built-in pump) 0 to 10 psi (gauge)
Pressure range (opt. external source) 0 to 30 psi (gauge)
Sensing bias <0.1 psi
Sensing resolution ±0.002 psi
Pressure accuracy ±7% 0.1 to 0.5 psi
±2% 0.5 to 1 psi
±1% greater than 1 psi
Pressure stability ±0.01 psi
Pressure channels 2
Max flow rate* 1000 mL/min

*total flow rate is divided among the two channels if operated simultaneously

Power consumption 12 W
Voltage 12 VDC
Dimensions 250 mm × 155 mm × 54 mm
Weight 815 g
Number of independent channels 2
Output pneumatic connections Push-to-connect fitting for OD 1/8”, ID 1/16" tubing (PA & PB)
Input pneumatic connection (optional) Push-to-connect fitting for OD 1/4”, ID 1/8" tubing (Pext)
Flow media compatability Non-corrosive, non-ionic gases such as air
Hardware connections USB