vivoChip-2x®
- Simple to set up and operate
- Immobilize up to 40 animals in parallel
- Chips available for L1–D5 stages
- Compatible with all microscopes
- Quantitative analysis in a few minutes
- No microfluidics experience required
Interested in purchasing vivoChip-2x devices? Request a quote →
The vivoChip®
C. elegans in vivo Imaging Solution
High-Resolution High-Content High-Throughput
C. elegans are an excellent tool for phenotypic screening of chemical libraries for drug discovery and toxicology, genetic screens, and human disease modeling. However, traditional techniques are unable to rapidly gather the high-resolution imaging data needed to screen large libraries.
vivoVerse’s solution: the vivoChip. A simple-to-use microfluidic device that allows anesthetic-free immobilization of up to 40 C. elegans or other nematodes for high-resolution imaging in any microscope.
What is the vivoChip-2x®?
The vivoChip-2x platform is a smaller scale version of our device designed for academic labs. It features the exact same technology as our larger devices and streamlines C. elegans immobilization by aligning them in parallel for high-resolution imaging. The platform has a proprietary design to immobilize animals in 40 parallel channels within 3 minutes, while orienting them in their lateral axis for high-resolution, high-speed imaging.
Request a Quote →Integrated Workflow
The vivoChip works with our vivoCube+ for fast, easy immobilization. The vivoCube+ is our microfluidics controller, designed to make using the vivoChips easy, and is required to use our chips.
To run an experiment with a vivoChip, capillary tubing with worms is inserted into the loading side of the chip. The tubing is then connected to the buffer reservoir bottle of the vivoCube+. Activating the vivoChip loading program starts a series of regulated pressure cycles, which load the C. elegans into the channels and orient them in their lateral orientation for ideal imaging conditions.
More about the vivoCube+ →
vivoChips for all C. elegans Stages
- vivoChip-2x L1-L2 for larval 1 to early larval 2 stage C. elegans.
- vivoChip-2x L2-L3 for late larval stage 2 to larval 3 stage C. elegans.
- vivoChip-2x L4-YA for larval 4 to young adult stage C. elegans.
- vivoChip-2x D1-D5 for day 1 to day 5 adult stage C. elegans.
vivoChips are also suitable for other types of nematode, including parasitic species.
Request a Quote →vivoChip-2x® Pack Contents:
Each pack contains:
- 4 vivoChips (8 independent immobilization devices)
- Tubing
- Connectors for connecting to the vivoCube.
